Bioprospecting Unripe Pericarp of Annona Reticulata for the Presence of Bioactive Compounds

Abstract

The present work was carried out with the objective of isolating and identifying biologically significant chemical compounds from the ethanol extract of unripe pericarp of Annona reticulata through bioassay-guided fractionation. Ethanol extract of unripe pericarp was prepared and fractionation was done using silica gel chromatography. Thin-layer chromatography profiling was done and a single compound was obtained. The compound was subjected to various spectroscopic techniques for the elucidation of its structure. The result of spectral analysis of the compound was compared with the reported data which led to propose the structure of bioactive polyphenolic component as ellagic acid. Ellagic acid is reported to have antiproliferative and antioxidant properties. It is also marketed as dietary supplement against cancer, heart disease, and other medical problems.

Keywords: Bioprospecting, ellagic acid, ethanolic extract, spectroscopic techniques

Cite this Article

V. S. Sangeetha, Adheena Elza Johns, Beena Lawrence. Bioprospecting Unripe Pericarp of Annona Reticulata for the Presence of Bioactive Compounds. Research & Reviews: A Journal of Life Sciences. 2018; 8(3): 44–49p