Open Access Open Access  Restricted Access Subscription or Fee Access

Free radical scavenging effect of various extracts of Root of Shirisha (Albizia lebbeck (L.)Benth.) by DPPH method

Purendra Singh

Abstract


The study of antioxidants and free radicals in biology is producing medical revolution that promises a new age disease and health management. The present study was performed to evaluate the in vitro antioxidant effect of the methanol, ethyl acetate, hydro alcohol and water extracts of Albizia lebbeck (L.) Benth. by using DPPH method. The ethyl acetate extract exhibited significant inhibition in DPPH free radical formation with IC50 values of 70.5206. The ethyl acetate extract showed potent activity on DPPH, which is compared to that of ascorbic acid (IC50 = 36.8582) taken as standard. The lesser IC50 value indicates larger antioxidant activity. The results of the present comprehensive analysis demonstrated that ethyl acetate extract of Albizia lebbeck (L.) Benth. is a viable source of nature antioxidant and might be exploited for functional foods and nutraceutical applications.

Keywords


Albizia lebbeck (L.) Benth. (Shirisha), Successive solvent extracts, DPPH free radical scavenging

Full Text:

PDF

References


(1) S.S. Yadav, Galib, P.K. Prajapti, H.C. Rudrappa, “Pharmacognostical and physicochemical investigations of Albizia lebbeck Benth. leaf”, International Journal of Science Innovations and Discoveries, Vol.1, Issue.2, pp.178-185, 2011.

(2) R.S. Troup, “The Silviculture of Indian Trees”, International Book Distributors, Dehra Dun, Vol.2, pp.466-473, 1921, (Reprinted in 1986).

(3) M. Hait, R.K. Burgah, C. Dass, “Chemotexonomic study of Albizia lebbeck”, Oriental Journal of Chemistry, Vol.25, Issue.2, pp.455-456, 2009.

(4) F. Mohammed, P. Singh, R. Irchhaiya, “Review of Albizia Lebbeck a Potent Herbal Drug”, International Research Journal of Pharmacy, Vol.3, Issue.5, pp.63-68, 2012.

(5) Muhammad ZIA-UL-HAQ, Shakeel Ahmad, Mughal Qayum, Sezai Ercisli, 2013, Compositional studies and antioxidant potential of Albizia lebbeck (L.) Benth. pods and seeds. Turkish Journal of Biology, 25-32.

(6) P.K. Basniwal, M.Suthar, G.S. Rathore, R. Gupta, V. Kumar, A. Pareek, D.Jain, 2009, In - vitro antioxidant activity of hot aqueous extract of Helicteres isora Linn. Fruits, 8(5): 483-487. Nature Product Radiance.

(7) Middleton E, Kandaswamy C, Theoharides TC, The effects of plant flavonoids on mammalin cells: implications for inflammation, heart disease and cancer, Pharmacol Rev. 2000, 52: 673-751.

(8) Pietta P, Simonetti P, Mauri P, Antioxidant activity of selected medicinal plants, J Agric Food Chem, 1998. 46:4487-4490.

(9) Lee KG, Mitchell AE, Shibamoto T, Determination of antioxidant properties of aroma extracts from various beans. J Agric Food Chem,2000, 48:4817-4820.




DOI: https://doi.org/10.37591/jomcct.v10i3.2415

Refbacks

  • There are currently no refbacks.