Synthesis and Antimicrobial Activity of New Heterocyclic Compound Containing 5-Bromobenzofuran

Authors

  • Basma Saad Baaiu Department of Chemistry, Faculty Science/University of Benghazi, Benghazi, Libya
  • Mansour Abdelsalam Department of Chemistry, Faculty Science/University of Benghazi, Benghazi, Libya

Keywords:

2-Acetyl-5-bromobenzofuran, pyridins, pyrazoles, chalcone solvent-free

Abstract

Several pyridine derivatives were synthesized via reaction of 2-acetyl 5-bromobenzofuran and 1,3-diphenyl-1 H-pyrazole-4-carbaldehyde 2 gave chalcone 3 which was exploited as a starting material. Structures of newly synthesized derivatives were confirmed by elemental analysis, spectral data, chemical transformation and alternative synthetic route whenever possible. Also, the newly synthesized derivatives were screened towards some microorganism.

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Published

2020-12-28

Issue

Vol. 11 No. 3 (2020)

Section

Articles

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