Grape Seed Extract: Potent Chemoprotective Agent: Phytochemical Analysis and GC-MS Study

P.A. Raajeswari, Suganya B.


Plant extracts or secondary metabolites have served as antioxidants in phytotherapeutic medicines to protect against various diseases for centuries. Phytochemicals are naturally occurring in the medicinal plants, leaves, vegetables and roots that have defence mechanism and protect from various diseases. Phytochemicals are primary and secondary compounds. Chlorophyll, proteins and common sugars are included in primary constituents and secondary compounds include terpenoids, alkaloids, quinines, flavonoids, sterols, saponins, tannins and phenolic compounds. In the present study, grape seeds, the waste material of the fruit was extracted with methanol, acetone and distilled water as solvent. The extracts were tested for presence of phytochemicals. Qualitative phytochemicals analysis showed presence of potent bioactive constituents such as polyphenols, terpenoids, flavonoids, tannins, alkaloids, cardiac glycosides, carbohydrates and phytosterols in grape seed extract. GC-MS analysis of methanolic grape seed extract revealed the presence of biologically significant compounds like 7-methoxy-2,2-dimethylchromone, hexadecanoic acid, 3-(4-hydroxy-3,5-dialkylphenyl)propanol 4-n-propylresorcinol and 2-hydroxycyclopentadecanone. The therapeutic effects of these compounds are yet to be studied.


Keywords: Grape, extracts, phytochemicals, GC-MS study

Cite this Article

Raajeswari PA, Suganya B. Grape Seed Extract: Potent Chemoprotective Agent: Phytochemical Analysis and GC-MS Study. Research & Reviews: Journal of Food Science and Technology. 2016; 5(3): 30–39p.

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