A Review on Phytochemical, Pharmacological and Unani Medicinal uses of mur (Commiphora myrrha)
Abstract
In the last few decades the use of plant products in medicines is getting popularized as the herbal medicines are usually cheap, easily available and have higher safety margins and lesser or no side effects due to natural origin. In Unani system of medicine mur (Commiphora myrrha) is mentioned as plant having medicinal properties on various system of human body. Various alkaloids have been identified in phytochemical analysis as well as different pharmacological properties have been noted in in-vitro and in-vivo studies. The aim of present review is to highlight the various Unani therapeutic uses as well as phytochemical and pharmacological reports on Commiphora myrrha gum resins.
Keywords: mur, phytochemical, pharmacological, unani, medicinal uses
Cite this Article
Haleema Aneesa K, Mariyam Roqaiya, Juveriya Naaz N. Bhusnur. A Review on Phytochemical, Pharmacological and Unani Medicinal uses of mur (Commiphora myrrha). Research & Reviews: Journal of Herbal Science. 2020; 9(1): 1–11p.
Keywords
References
Öktemer T, Ipçi K, Muluk N B and Cingi C, A pastille combining myrrh tincture, peppermint oil and menthol to treat the upper airway. Curative treatment of primary (spasmodic) dysmenorrhoea, ENT Updates 2015, 5(3), 128-131.
Alizadeh R, Abedi G, Ashrafi J and Mansoori K, Effect of Commiphora Myrrha on Sciatic Nerve Regeneration, International Journal of Biology and Allied Science, 2014, 3(9), 2108-2118.
Gadir S A and Ahmed I M, Commiphora myrrha and Commiphora africana essential oils, Journal of Chemical and Pharmaceutical Research, 2014, 6(7), 151-156.
Sairkar P K, Sharma A and Shukla N P, SCAR Marker for Identification and Discrimination of Commiphora wightii and C. myrrha. Molecular Biology International, 2016, Article ID 1482796, 10 pages http://dx.doi.org/10.1155/2016/1482796
Su S, Duan J, Chen T, Huang X, Shang E, Yu L, et al, Frankincense and myrrh suppress inflammation via regulation of the metabolic profiling and the MAPK signaling pathway, Sci. Rep, 2015, doi: 10.1038/srep13668.
Albrecht U, Müller V, Schneider B and Stange R, Efficacy and safety of a herbal medicinal product containing myrrh, chamomile and coffee charcoal for the treatment of gastrointestinal disorders: a non-interventional study, BMJ Open Gastro 2014, 1, 1-7. doi:10.1136/bmjgast-2014-000015
Shulan Su, Wang T, Chen T, Duan J, Yu L and Tang Y, Cytotoxicity activity of extracts and compounds from Commiphora myrrha resin against human gynecologic cancer cells, Journal of Medicinal Plants Research, 2011, 5(8), 1382-1389.
Wang X, Kong F, Shen T, Young C Y F, Lou H and Yuan H, Sesquiterpenoids from myrrh inhibit androgen receptor expression and function in human prostate cancer cells, Acta Pharmacologica Sinica, 2011, 32, 338-344.
Omer S A, Adam S E I and Mohammed O B, Antimicrobial Activity of Commiphora myrrha Against Some Bacteria and Candida albicans Isolated from Gazelles at King Khalid wildlife Research centre, Reseach Journal of Medicinal plant, 2011, 5(1), 65-71.
Hanuš L O, Řezanka T, Dembitsky V M and Moussaieff A, MYRRH – COMMIPHORA CHEMISTRY, Biomed. Papers, 2005, 149(1), 3-28.
Olivier D K and vanWyk B E, Bitterness values for traditional tonic plants of southern Africa, Journal of Ethnopharmacology, 2013, 147, 676-679.
Abdul-Ghani R A, Loutfy N and Hassan A, Myrrh and trematodoses in Egypt: An overview of safety, efficacy and effectiveness profiles, Parasitology International, 2009, 58, 210-214.
Ghani N R, Khazainul advia, (Idarae Kitabul Shifa New Delhi), YNM, 1229-1230.
Ben-Yehoshua S, Borowitz C and Hanus L O, Frankincense, Myrrh, and Balm of Gilead: Ancient Spices of Southern Arabia and Judea, Horticultural Reviews, 2012, 39(1), 1-76.
Ibn baitar, Jamiul mufradatul Advia wa Agzia, Vol IV, (CCRUM Delhi), 2003, 319.
Soni P D, Upadhyay S U, and Upadhyay U M, A Review on Commiphora myyrha, An International Journal of Pharmaceutical Sciences, 2013, 4(3), 171-205.
Anonymous, Standardisation of single drugs of unani medicine, Part II, 1st Ed, (CCRUM New Delhi), 1992, 222-225.
Nadkarni K M, Indian Plants and Drugs, (Asiatic Publishing House New Delhi), 2010, 49.
Prajapathi N D, Purohit S S, Sharma A K and Kumar T, A Handbook of Medicinal Plants, (Agrobios India), 2003, 164-165.
Tariq N A, Tajul Mufradat, (Idara Kitab-ul-Shifa New Delhi), 2004, 680-681.
Ammar N M, El-Hawary S S, Mahdy A A, Hussein R A and Okino T, Phytochemical Study of the Biologically Active Fractions of the Oleo-gum-resins of Boswellia carteri and Commiphora myrrha, Advances in Environmental Biology, 2013, 7(9), 2573-2583.
Mekonnen Y, Dekebo A and Dagne E, Toxicity Study in Mice of Resins of Three Commiphora Species, Ethiop. J. Sci, 2003, 26(2), 151-153.
Kabeerudeen M, Maghzanul Mufradat, 2nd Ed, (Idarae Kitabul Shifa New Delhi), 2010, 380-381.
Razi A B M Z, Maqala fi Abdal al-advia al Mustamala fi al-Tib wa al-Ilaj Kitabul Al Abdal, (CCRUM New Delhi), 1999.
Ibn Rushd, Kitabul Kulliyath, Ed.2nd, (CCRUM New Delhi), 1987, 304.
Abdul Hakeem M, Busthanul mufradath, (Idara Kitab-ul-Shifa New Delhi), 1999, 143-144.
Yaser A J, Muneer A, Abdelhafid B, Daoudi C S and Hammadi A L, Chemical and Phyto chemical Analysis of Some Antidiabetic Plants in Yemen, International Research Journal of Pharmacy, 2013, 4(9), 72-76.
Singh G K and Bhandari A, Textbook of pharmacognosy, Ed. 1st, (CBS Publishers New Delhi), 2016, 145.
de Rapper S, Vuuren S F V, Kamatou G P P, Viljoen A M and Dagne E, The Additive and Synergistic Antimicrobial Effects of Select Frankincense and myrrh oils – A Combination from the Pharaonic Pharmacopoeia, Letters in Applied Microbiology, 2012, 54, 352-358.
Bhattacharjee S K, Handbook of Medicinal Plants, 5th Ed, (Pointer Publishers Jaipur), 2012, 111-112.
Shaik J, Vishakha K and Ramyasree D, Evaluation of antibacterial activity of Commiphora myrrha against antibiotic resistant clinical pathogens, Indian Journal of Pharmaceutical and Biological Research, 2015, 3(3), 7-11.
Mohamed A A, Ali S I, EL-Baz F K, Hegazy A K and Kord M A, Chemical composition of essential oil and in vitro antioxidant and antimicrobial activities of crude extracts of Commiphora myrrha resin, Industrial Crops and Products, 2014, 57, 10-16.
EL-Kamali1 H H, Burham B O and EL-Egami A A B, Determination of Volatile Compounds from Commiphora myrrha (Nees) Engl. Resin Marketed in Central Sudan by GC/MS, American Journal of BioScience, 2015, 3(4), 117-120.
Al-Abdalall A H A, Antibacterial Properties and Phytochemical Analysis of Aqueous extract of oleo-gum resins of Commiphora myrrha and Commiphora molmol, Canadian Journal of Pure and Applied Sciences, 2013, 7(2), 2315-2323.
Anand S, Rajan M, Venkateshbabu N, Kandaswamy D, Shravya. Y and Rajeswari K, Evaluation of the Antibacterial Efficacy of Azadirachta indica, Commiphora myrrha, Glycyrrhiza glabra against Enterococcus faecalis using Real Time PCR, The Open Dentistry Journal, 2016, 10, 160-165.
Chandrasekharnath N, Mahlakshmi Y V, Jayalakshmi L, Venkanna B, Uma A, Screening and isolation of bioactive factors from Commiphora myrrha and evaluation of their antimicrobial activity, International Journal of Engineering Research and Applications, 2013, 3(2), 1291-1294.
Abd-Ulgadir K S, El Tahir A S, Ahmed H H, El Shiekh H E, Rakaz M A, Abosalif KO, Abdelsalam K A and Satti A B, AN In Vitro ANTIMICROBIAL POTENTIAL OF VARIOUS EXTRACTS OF COMMIPHORA MYRRHA, Journal of Biomedical and Pharmaceutical Research, 2015, 4(2), 15-19.
Ahmed K M, Suleiman E A and Ahmed A M, In vitro Antifungal activity of Commiphora myrrha extract against Aspergillus species, Imperial Journal of Interdisciplinary Research, 2016, 2(12), 1071-1077.
Al-Kazzaz M A, Effects of myrrh derivative (Mirazid) compared with praziquantel on worm characteristics and serum liver biomarkers in Schistosoma mansoni infected mice, Journal of Natural Products and Pharmacological Research, 2017, 1(1): 15-19.
Attia R A H, Mahmoud A E, Farrag H M M, Makboul R, Mohamed M E and Ibraheim Z, Effect of myrrh and thyme on Trichinella spiralis enteral and parenteral phases with inducible nitric oxide expression in mice, Mem Inst Oswaldo Cruz, Rio de Janeiro, 2015, 110(8), 1035-1041.
Al Marby A, Ejike C E C C, Nasim M J, Awadh Ali N A, Al badani R A, Alghamdi G M A, et al, Nematicidal and antimicrobial activities of methanol extracts of 17 plants, of importance in ethnopharmacology, obtained from the Arabian Peninsula, Journal of Intercultural Ethnopharmacology, 2016, 5(2), 114-121.
Singh R K, Joshi V K and Gambhir S S, Anti-Inflammatory Activity of Some Traditional Medicinal Plants, Ancient Science of Life, 1998, 18(2), 160-164.
Kim M S, Bae G S, Park K C, Koo B S, Kim B J, Lee H J, et al, Myrrh Inhibits LPS-Induced Inflammatory Response and Protects from Cecal Ligation and Puncture-Induced Sepsis, Evidence-Based Complementary and Alternative Medicine, 2012, doi:10.1155/2012/278718.
Su S, Wang T, Duan J A, Zhou W, Hua Y Q, Tang Y P, et al, Anti-inflammatory and analgesic activity of different extracts of Commiphora myrrha, J Ethnopharmacol, 2011, 134(2), 251-258.
Vissiennon C, Goos K H, Goos O and Nieber K, Antispasmodic Effects of Myrrh due to Calcium Antagonistic Effects in Inflamed Rat Small Intestinal Preparations, Planta Med, 2015, 81, 116-122.
Helal E G E, Mahmoud A, El-Badawy E E and Kahwash A A, Effect of Commiphora myrrha extract on some physiological parameters and histological changes in diabetic albino rats, The Egyptian Journal of Hospital Medicine, 2005, 20, 148-162.
Xu J, Guo Y, Zhao P, Guo P, Ma Y, Xie C, et al, Four new sesquiterpenes from Commiphora myrrha and their neuroprotective effects, Fitoterapia, 2012, 83(4), 801-805.
Germano A, Occhipinti A, Barbero F and Maffei M E, A Pilot Study on Bioactive Constituents and Analgesic Effects of MyrLiq, a Commiphora myrrha Extract with a High Furanodiene Content, BioMed Research International 2017, Article ID 3804356, 11 pages available at https://doi.org/10.1155/2017/3804356
Ghada Mansour, Soliman Ouda and Ahmed Shaker, Clinical efficacy of new aloe vera- and myrrh-based oralmucoadhesive gels in the management of minor recurrent aphthous stomatitis: a randomized, double-blind, vehicle controlled study, Journal of Oral Pathology and Medicine, 2013, 2-6.
Langhorst J, Westendorf A, Knopp M, Schneider S, Goos K, Albrecht U, et al, Randomized, double-blind, double dummy trial of myrrh, chamomile, coffee charcoal compared to mesalazine in maintaining remissionin ulcerative colitis, BMC Complementary and Alternative Medicine, 2012, 12(Suppl1), 27.
Refbacks
- There are currently no refbacks.
Copyright (c) 2020 Research & Reviews: Journal of Herbal Science