Kumkuma Nasya for Migraine: Randomized Double-blind Study with an Insight into Vatavriddhi and Caloric Values

Abstract

Introduction: Ardhavbhedaka Roga of Ayurveda can be correlated with migraine. Exaggeration of Vata plays the most important role in the pathogenesis of pain. We used a model of low caloric values, as it is suitable and conclusive for the assessment of Vatavriddhi. As per Sharangadhar Samhita, Kumkuma (saffron) Nasya (nasal administration) is said to be effective in Ardhavabhedaka (migraine), owing to the exaggerated of Vata and Rakta. Aim: Therefore, this study was aimed at checking the efficacy of Kumkuma Nasya on Ardhavbhedaka Roga with special reference to caloric values of Vatavriddhi (pain model). Settings and Design: This research is a randomized, double-blind, placebo-control trial, conducted on 60 patients of migraine with lower caloric values. Methods and Material: Kumkuma Nasya 1.98 ml (1 ml in each nostril) daily up to 9 days, once a day at evening between 4 and 5 pm was administered through the nasal route as per standard operative procedure of Nasya. Headache severity levels were analysed using the visual analogue scale, and caloric values of Vatavriddhi were analyzed on 0th, 10th and 40th day. Statistical Analysis Used: Test of proportionality and ‘T’ test were used for data analysis. Results: Statistically significant reduction were observed in the pain level (Ativedana) of patients with Ardhavabhedaka Roga in visual analogue scale, statistically significant increase in caloric values was observed in the experimental group. Conclusions: 1.98 ml (32 Bindu) dose of Kumkuma Nasya relives pain in migraine. Also, it was found significant to increase in caloric values of Vatavriddhi.