Diabetes and the Interrelationship Between Genes Significantly Related to it: A Brief Study
DOI:
https://doi.org/10.37591/rrjols.v9i1.1482Keywords:
Diabetes, Non-communicable diseases, Genes, Phylogenetic treeAbstract
Diabetes, one of the key non-communicable diseases (NCDs), is increasing its grip all over the world in rapid pace. In India, the scenario is more severe and it is estimated that this country will become diabetes capital of the world soon. Although the vast array of research articles published worldwide has helped to understand the etiology of this disease to a great extent, a huge amount of research is still pending. In this study, we have focussed on a few genes which have been shown to have significant impact on diabetes in previous reports. We have tried to understand how they are linked with each other, including their evolutionary paths. Our study indicated that most of these genes are closely related to each other and may have a common origin.
Keywords: Diabetes, non-communicable diseases (NCDs), genes, phylogenetic tree
Cite this Article
Malavika Bhattacharya, Rajika Roy Chowdhury. Diabetes and the Interrelationship Between Genes Significantly Related to it: A Brief Study. Research & Reviews: A Journal of Life Sciences. 2019; 9(1): 59–61p.
References
Reddy KS, Shah B, Varghese C, Ramadoss A. Responding to the threat of chronic diseases in India. Lancet. 2005; 366: 1744-1749p.
Terzic A and Waldman S. Chronic diseases: the emerging pandemic. Clin. Transl. Sci. 2011; 4(3); 225–226p.
World Health Organization: Global action plan for the prevention and control of noncommunicable diseases 2013-2020. In. Edited by WHO. Geneva, Switzerland: WHO. 2013; 55.
WHO report on Non communicable diseases in the South-East Asia Region, Situation and Response, 2011; Chapter 1
Geneau R, Stuckler D, Stachenko S, McKee M, Ebrahim S, Basu S, Chockalingham A, Mwatsama M, Jamal R, Alwan A. Raising the priority of preventing chronic diseases: a political process. Lancet. 2010; 376(9753):1689–1698p.
Mathers CD, Loncar D. Projections of Global Mortality and Burden of Disease from 2002 to 2030. Plos Medicine. 2006; 3(11): e442.
Report of the working group on disease burden for 12th five year plan. [Online]. http://planningcommission.gov.in/aboutus/committee/wrkgrp12/health/WG_3_2non_communicable.pdf. 2011.
Hwang D, Lee IY, Yoo H, Gehlenborg N, Cho JH et al. A systems approach to prion disease. Molecular Systems Biology. 2009; 5: 252.
Hood L, Heath JR, Phelps ME, Lin B. Systems biology and new technologies enable predictive and preventative medicine. Science. 2004; 306: 640-643p.
Bernardo DD, Thompson MJ, Gardner TS, Chobot SE, Eastwood EL et al. Chemogenomic profiling on a genome-wide scale using reverse-engineered gene networks. National Biotechnology. 2005; 23: 377-383p.
Li BQ, Huang T, Liu L, Cai YD, Chou KC. Identification of colorectal cancer related genes with mRMR and shortest path in protein-protein interaction network. PLoS One. 2012; 7: e33393.
Dereeper A, Audic S, Claverie JM, and Blanc G. BLAST-EXPLORER helps you building datasets for phylogenetic analysis. BMC Evol. Biol. 2010; 10: 8.
Downloads
Published
Issue
Section
License
Declaration and Copyright Transfer Form
(to be completed by authors)
I/ We, the undersigned author(s) of the submitted manuscript, hereby declare, that the above manuscript which is submitted for publication in the STM Journals(s), is not published already in part or whole (except in the form of abstract) in any journal or magazine for private or public circulation, and, is not under consideration of publication elsewhere.
- I/We will not withdraw the manuscript after 1 week of submission as I have read the Author Guidelines and will adhere to the guidelines.
- I/We Author(s ) have niether given nor will give this manuscript elsewhere for publishing after submitting in STM Journal(s).
- I/ We have read the original version of the manuscript and am/ are responsible for the thought contents embodied in it. The work dealt in the manuscript is my/ our own, and my/ our individual contribution to this work is significant enough to qualify for authorship.
- I/We also agree to the authorship of the article in the following order:
Author’s name
1. ________________
2. ________________
3. ________________
4. ________________
| We Author(s) tick this box and would request you to consider it as our signature as we agree to the terms of this Copyright Notice, which will apply to this submission if and when it is published by this journal. |