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Structure and Origin Insight of Recent Corona Virus with Ongoing Therapeutic Approach

Ajeet singh


Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is highly transmissible zoonotic virus that was initially reported in late 2019 in Wuhan, China. Presently, it has infected approximately 1.5 million person and responsible for more than 0.1 million death across the world. It is likely evolved from bats and pangolin and genetically different from SARS-CoV-1, responsible for SARS disease. In present review, we have discussed the recent finding of its origin from bats and pangolin, its phylogenetic comparison from other coronavirus and ongoing therapeutic approaches against the fight of SARS-CoV-2.


Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), Non-structural protein (NSPs), human angiotensin converting enzyme-2 (hACE2), TMPRSS2, receptor binding domain (RBD)

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