Hydrotropes as Effective Reaction Media for the Synthesis of Carbamazepine

Authors

  • Manohar V. Lokhande Department of Chemistry, Sathaye College, Vile Parle (E), Mumbai-400057, India
  • Jagannath J. Kadam Department of Chemistry, Bharati Vidyapeeth College of Engineering, Navi Mumbai-400614, India
  • Ajay Patil Department of Chemistry, Bhavan’s College, Andheri (W), Mumbai-400058, India
  • Vijay G. Bhawe Department of Chemistry, Bhavan’s College, Andheri (W), Mumbai-400058, India

DOI:

https://doi.org/10.37591/jomcct.v3i1-3.2030

Keywords:

Hydrotropes, xylene sulfonic acid (XSA), cumene sulfonic acid (CSA), (n-BBSA), n-Butyl benzene sulfonic acid (n-BBSA), isobutyl benzene sulfonic acid (I-BBSA), 1HNMR, IR.

Abstract

The paper describes the synthesis of Carbamazepine. It is used as an anticonvulsant and antiemetic agent. It is also used in the treatment of pain associated with trigeminal neuralgia, often within 24 to 48 hr. The synthesis of Carbamazepine was carried out using four different hydrotropes. The effects of hydrotropes on yield, rate constant and activation energy at various temperatures and concentrations were studied

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Published

2019-05-04

Issue

Vol. 3 No. 1-3 (2012)

Section

Articles

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