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Synthesis Spectral Characterisation and Biological Activity of Hetero-cyclic Compound of 2-Imidazolones

Murlidhar K. Rahangdale, Suraj Deshmukh

Abstract


Because of the wide range of applications for 2-imidazolones, they have achieved enormous importance in human life. Although there are other methods for generating 2-imidazolones, the bulk of them required an 8 to 10 hour reflux period. As a result, the suggested study was done to develop a simple process for the synthesis of 2-imidazolones and to improve product yield by using Zeolite as a catalyst. The work described here addresses the synthesis of several substituted 2-imidazolones using substituted benzoins and urea as solvents and Zeolite as a catalyst. The work presented here discusses the synthesis of a number of substituted 2-imidazolones using substituted benzoins and urea as solvents and Zeolite as a catalyst. Substituted benzoins have been produced from aromatic aldehydes through condensation in the presence of aqueous NaCN. Chemical characteristics, elemental analysis, and spectrum analysis were used to characterize produced substances.

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References


DAmbrosia M, Guerried A, Debitus C, Chem. Commun,1993, 1305.

Koswatta PB, Lovely CJ, Nat. Products Reports, 28, 2011, 511-528.

Forte PB, Malgesini B, Piuttic, Papeo G, Mar. Dougs, 7, 2009, 705-5.

Glass D, Buschauer A, Tenar H, Will Saheb L, Krause EG, Arch Pharma (Weinheim) 328(10),1995, 709-19.

Stoffel PJ and Speziale AJ, J.Org.Chem., 27(9), 1962, 3079.

Jie-Fei Cheng, Christopher Kaiho, Mi Chen, Thomas Arrhenius and Alex Nadzan, Tetrahedron, 43,2002, 4571-4573.

Inas M AlNashef, MohdAHashim, Farous S Mjalli, Mohammad Q Al-haj Ali, MaanHayyan,Tetrahedron, 51, 2002, 1976-1978.

Congiu C, Cocco MT and Onnis V; Bioorg. Med. Chem. Lett., 18, 2008, 989.

Bauer AW, WMMJC Sherris and M Truck. Antibiotics susceptibility test by a standardized single disc method Am.J.Clin.phthol, 1966; 45: 493-96.

Maria C. DiPoto and Jimmy Wu.Org.Lett. 2018,20,3, 499-501.

Qing Liu, Xiao Meng, Ya Li, Cai-Ning Zhao, Guo-Yi Tang, and Hua-Bin Li. Int J MolSci.2017 Jun; 18(6): 1283

D. H. Tambekar and S. B. Dahikar. J Adv PharmTechnol Res,2011 Jan-Mar; 2(1): 24–29.


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