Synthesis and Evaluation of Chalcone Derivatives and Schiff bases derivatives as Antibacterial

Authors

  • Nada Abdoulnasser Elsharif University of Benghazi
  • Mohamed Alnaily Department of Chemistry, Faculty of Science, University of Benghazi, Benghazi, Libya
  • Amnnah Loujanqi University of Kufra - Faculty of Science - Department of Biology

DOI:

https://doi.org/10.37591/jomcct.v9i3.1514

Keywords:

, chalcones derivates, Claisen –Schmidt condensation, Schiff base derivates Antibacterial agents

Abstract

Abstract

Six substituted chalcones have been synthesized by condensing benzaldehyde derivatives with acetophenone in dilute ethanolic sodium hydroxide solution at room temperature according to Claisen-Schmidt condensation. In addition, four of Schiff bases have been prepared via imine condensation between substituted benzaldehyde firstly with (3) 2-aminophenol, secondly, with phenylhydrazine. Moreover, study the efficient of synthesized compounds as antibacterial agents were evaluated. The structures of the synthesized compounds were confirmed by the melting points depending on known literature. The new in our research is that we have evaluated and compared these compounds against some kinds of bacteria.  

 

Keywords: Chalcones derivates, Claisen-Schmidt condensation, Schiff base derivates, Antibacterial agents

Cite this Article

Nada Elsharif, Mohamed Alnaily, Amnnah Loujanqi, Synthesis and Evaluation of Chalcone Derivatives and Schiff bases Derivatives as Antibacterial. 2018. Journal of Modern Chemistry & Chemical Technology. 2018; 9(3): 1–7p.

Downloads

Published

2019-01-28

Issue

Vol. 9 No. 3 (2018)

Section

Research Articles

License

Declaration and Copyright Transfer Form

(to be completed by authors)

I/ We, the undersigned author(s) of the submitted manuscript, hereby declare, that the above manuscript which is submitted for publication in the STM Journals(s), is not published already in part or whole (except in the form of abstract) in any journal or magazine for private or public circulation, and, is not under consideration of publication elsewhere.

  • I/We will not withdraw the manuscript after 1 week of submission as I have read the Author Guidelines and will adhere to the guidelines.
  • I/We Author(s ) have niether given nor will give this manuscript elsewhere for publishing after submitting in STM Journal(s).
  • I/ We have read the original version of the manuscript and am/ are responsible for the thought contents embodied in it. The work dealt in the manuscript is my/ our own, and my/ our individual contribution to this work is significant enough to qualify for authorship.
  •  I/We also agree to the authorship of the article in the following order:

Author’s name                                    

 

1. ________________

2. ________________

3. ________________

4. ________________

 

We  Author(s) tick this box and would request you to consider it as our signature as we agree to the terms of this Copyright Notice, which will apply to this submission if and when it is published by this journal.