Open Access
Subscription or Fee Access
A Comprehensive Review on Biological Activities of Caesalpinia crista L. (Caesalpinaceae)
Abstract
Caesalpinia crista L., a member of the Caesalpinaceae family, is used for medicinal purposes. It's a thorny bush that grows in the tropics of India, Sri Lanka and the Andaman and Nicobar Islands, but can be found all over the world. It has a long history of importance as a therapeutic agent in the traditional plant system of India. This is a highly valued medicinal plant used in the ancient medical system since its entirety has healing powers. Antidiarrheal, anti-tumor, anti-diabetic, anti-colic, anticonvulsant, anti-helmintic, anti-fertility, anti-inflammatory, anxiolytic, analgesic, Immunomodulatory and anti-viral properties have all been attributed to this plant. Alkaloids, terpenoids, flavonoids, glycosides and saponins have all been identified through phytochemical study. This review seeks to review the existing information on Caesalpinia crista L. by summarizing its pharmacological effects, chemical components and pharmacognostic features.
Keywords
References
Nwachukwu C, Okere C, Nwoko MC, Identification and Traditional uses of some common Medicinal Plants in Ezinihitte Mbaise L.G. A of Imo State Nigeria. 1553-9873; 2010.
Singh V, Pramod K. Review on Pharmacological properties of C.bonduc L. Int J Med Arom Plants. 2012; 2: 515-30p.
Al-Snafi A E. Pharmacological effects of Allium species grown in Iraq- An overview. Intern J Pharma and Healthcare Res. 2013; 4: 132-47p.
Ghawade S. Pharmacological Review On Caesalpinia Crista: An Overview. Pharmatutor-art. 2011; 1175p.
Mandal N., Mandal S, Hazra B, et al. Assessment of the antioxidant and reactive oxygen species scavenging activity of methanolic extract of Caesalpinia crista leaf. Evidence-Based Complementary and Alternative Medicine. 2009; 1-11p.
Ramesh B, Girish T, Raghavendra R, et al. Comparative study on anti-oxidant and anti-inflammatory activities of Caesalpinia crista and Centella asiatica leaf extracts. J Pharm Bioallied Scie. 2014; 6(2): 86–91p.
Afrin S, Pervin R, Sabrin F, et al. Assessment of antioxidant, antibacterial and preliminary cytotoxic activity of chloroform and methanol extracts of Caesalpinia crista . Leaf. Bang J. Bot. 2016; 45(5): 1061-8p.
Kumar R, Narasingappa R, Joshi C, et al. Caesalpinia Crista Linn. Induces protection against DNA and membrane damage. Pharmacog. Magazine. 2017; 13(50): 250-257p.
Kumar A, Dhule M. A conceptual study on latakaranja: a critical drug review. World J of Adv Healthcare Research. 2019; 3(3): 78-85p.
Sodhi J, Kaur A, Shrivastava B, et al. Antioxidant potential of Caesalpinia crista seeds. J of critical reviews. 2020; 7(18): 3053-6p.
Srinivasa C, Kengaiah J, Nandish S, et al. Caesalpinia crista coat extract protects red blood cell from sodium nitrite-induced oxidative stress and exhibits antiplatelet activity. Inter J Haemos Thromb. 2020; 31(5): 293-302p.
Mobin L, Saeed S, Ali R, et al. Antibacterial antioxidant and phenolic fractions analysis of Caesalpinia crista seed coat extract and its different fractions. Pakistan Journal of Botany. 2021; 53(2): 597-603p.
Patil KS, Wound healing activity of the seed kernels of Caesalpinia crista Linn. J of natural remedies. 2005; 5(1): 26-30.
Satnami D, Yadava R. Potential phytochemical from Caesalpinia crista Linn. Res J of Phytochemistry. 2011; 5: 22-31p.
Usha P, Sharma M. Antiviral activity of lathakaranja (Caesalpinia crista L.) crude extracts on selected animal viruses. Global J Res on Medicinal Plants & Indigenous Medicine. 2012; 1(9): 440-7p.
Kumar A, Garg V, Chaudhary A, et al. Isolation, characterisation and antibacterial activity of new compounds from methanolic extract of seeds of Caesalpinia crista L. (Caesalpinaceae). Nat Prod Res. 2014; 28(4): 230-8.
Mobin L, Saeed S, Ali R, et al. Antibacterial and antifungal activities of the polyphenolic fractions isolated from the seed coat of Abrus precatorius and Caesalpinia crista. Natural Product Research, 2018; 32(23): 2835-9p.
Banskota A, Attamimi F, Usia T, et al. Novel norcassane-type diterpene from the seed kernels of Caesalpinia crista. Tetrahedron Letters, 2003; 44(36): 6879-82p.
Linn T, Awale S, Tezuka Y, et al. Cassane- and norcassane-type diterpenes from Caesalpinia crista of Indonesia and their antimalarial activity against the growth of Plasmodium falciparum. J Natural Prod. 2005; 68(5): 706-10p.
Kadota S, Linn T, Tezuka Y, et al. Constutuents of Caesalpinia crista from Indonesia. Chem. Pharma. Bull. 2006; 54(2): 213-8p.
Kadota S, Kaluni S, Awale S, et al. Antimalarial activity of cassane- and norcassane-type diterpenes from Caesalpinia crista and Their Structure–Activity Relationship. Biol. Pharma Bull. 2006; 29(5): 1050-52p.
Zaman K, Chetia D. Pharmacognostic investigation and evaluation of antimalarial activity on the leaves of Caesalpinia crista (L) Roxb. an antimalarial medicinal plant of Assam. Current trends in pharmaceutical research. 2013; 2(1):1-2p.
Jabbar A, Zaman M, Iqbal Z, et al. Anthelmintic activity of Chenopodium album (L.) and Caesalpinia crista (L.) against trichostrongylid nematodes of sheep. Journal of Ethnopharmacology. 2007; 114(1): 86-91p.
Singhal A. Chromatographic analysis and anthelmintic activity of the seed oil of Caesalpinia crista, Asian J of Chem. 2017; 9(5): 3577-80p.
Shah S, Khan M, Khan S. Comparative anthelmintic efficacy of Caesalpinia Crista, Nigella Sativa and Oxfendazole in broilers with experimentally induced Ascaridia Galli Infection. Universal Journal of Clinical Medicine, 2014; 2(3): 53-7p.
Bhardwaj L, Chandrul K, Sharma U. Evaluation of anthelmintic activity of Caesalpinia crista Linn. seed extract. Biology. 2016; 5(4):15-20p.
Suryawanshi HP, Patel MR. Anthelmintic activity of Caesalpinia crista (linn) leaves against Pherituma posthuman. Inter J Pharma Sci. 2017; 8(3):26-32p.
Kailani S, Shoaib M, Ashraf M. Antifasciolic efficacy of indigenous plant drugs: kalonji shahterah and karanjwa in buffaloes. Pakistan J of Pharmaceutical Scie. 1995; 8(1): 17-27p.
Maqbool A, Sikandar H, Tanveer A. Comparative efficacy of various indigenous and allopathic drugs against fasciolosis in buffaloes. Veterinarski arhiv. 2004; 74(2): 107-14p.
Durrani A, Khosa M, Ayaz M, et al. Therapeutic efficacies of Fumaria parviflora, Caesalpinia crista and oxyclozanide against fasciolosis in naturally infected sheep in Rawalakot. World Journal of Zoology. 2015; 10(2): 118-23p.
Qureshi A, Tanveer A, Sheikh N. Effect of Saussurea lappa (roots) and Caesalpinia crista (seeds), on Serum Protein Profile of Fasciola infected Buffaloes, in comparison with Triclabendazole. Biologia. 2016; 62(1): 121-6p.
Qureshi AW. Anti-fasciolic efficacy of some medicinal plants in comparison with triclabendazole in naturally occurring infected buffaloes. in 5th International conference and exhibition traditional medicine November 05-06, London, UK. 2018.
Reddy M, Kuber B. Antiplasmodial activity of Caesalpinia crista seed extracts. J of Drug Delivery and Thera. 2018; 8(5): 354-7p.
Akhtar M, Javed I, Hayat C, et al. Efficacy and safety of Caesalpinia crista seeds its extracts in water and methanol against natural Neoascaris vitulorum infection in buffalo calves. Pakistan Veterinary Journal. 1985; 5(4): 192-6p.
Javed I, Akiitar M, Raiimant K, et al. Comparative anthelminthic efficacy and safety of Caesalpinia crista seed and piperazine adipate in chickens with artificially induced Ascaridia galli infection. Acta Velerunuria. 1994; 42(1): 103-9p.
Tian Q, Ou Y, He X, et al. One new antitumor cassane-type diterpene from Caesalpinia crista. Nat Prod Rese, 2013; 27(6): 537-40p.
Das B, Srinivas Y, Sudhakar C, et al. New diterpenoids from Caesalpinia species and their cytotoxic activity. Bioorganic and Medicinal Chemistry Letters, 2010; 20(9): 2847-50.
Sardar R, Mandal N. In vitro cytotoxic effect of hydroalcoholic extracts of medicinal plants on Ehrlich's Ascites Carcinoma (EAC). Inter J of Phytomedicine. 2011; 3(2011): 370-80p.
Bodakhe H, Agrawal A, Agrawal A, et al. Anticancer study on alcoholic extract of Caesalpinia crista root bark extract. J of Pharma Res. 2011; 11(1): 126-8p.
Jalal M, Shamim M, Mohammed D, et al. Study on cytotoxic activity of Clerodendrum inerme and Caesalpinia crista by Brine Shrimp Lethality Bioassay. Inter J Inno and Applied Stud. 2014; 8(4): 1574-80p.
Liu Q, Huang L, Zhang L, et al. Two new cassane-type diterpenes from the seeds of Caesalpinia crista. J of Asian Nat Prod Res, 2015; 17(11): 1073-8p.
Chauhan P, Gupta N, Mm S. Evaluation of anti-ulcer activity of Caesalpinia crista linn. seeds on pylorus ligation and indomethacine induced gastric lesions in albino rats. Int J Res Pharm Sci. 2015; 5(4): 9-13p.
Zaware B, Gilhotra R, Chaudhari S. A review on therapeutic potential of Caesalpinia crista. Res J Pharma, Biolo and Chem Sci. 2018; 9 (5): 555-66p.
Gupta N. Antidiabetic activity of seed extracts of Caesalpinia crista Linn. in experimental animals. Afri J of Pharm and Pharmac. 2013; 7(26): 1808-13p.
Novida P, Isna R, Aziz I, et al. Antidiabetic Activity of Kemrunggi (Caesalpinia crista L.) Seeds Infusion in Albino Rats (Rattus norvegicus Berkenhout, 1769) Hyperglycaemic 2018. Inter J Pharmac Rese. 2018; 10(4): 389-93p.
Sulfahri A, Iskandar I, Wardhani R. In silico approach of antidiabetic compounds from Caesalpinia crista seed through docking analysis and ADMET predictions. Journal of Physics: Conference Series. 2019; 1341(2): 1-5p.
Naresh S, Kaur R, Arora R. et al. Phytochemical investigation of Caesalpinia crista seed extract for their therapeutic potential. Research J of Medicinal Plant. 2012; 6(1): 100-7p.
Reddy SM, Ramyakuber B. Evaluating the anti-inflammatory potential of isolated constituents from seeds of Caesalpinia crista. J of pharma res. 2017; 6(2): 77-8p.
Ishan S, Nakul G, Safhi M, et al. Antipyretic activity of Caesalpinia crista Linn. seeds extract in experimental animals. Inter J of Current Research. 2013; 5(5): 1202-5p.
Kshirsagar S, Sakarkar D, Deshpande S. Learning and memory enhancing activity of ethanolic extract of dried seed kernels of Caesalpinia crista Lin. in albino mice. Pharmacie Globale (IJCP) 2012; 9(4): 1-6p.
Ramesh B, Indi S, Rao K. Anti-amyloidogenic property of leaf aqueous extract of Caesalpinia crista. Neuroscience Letters. 2010; 475(2): 110-14p.
Ravi S, Ramesh B, Mundugaru R, et al. Multiple pharmacological activities of Caesalpinia crista against aluminium-induced neurodegeneration in rats: Relevance for Alzheimer’s disease. Envir Toxicology and Pharma. 2018; 58: 202-11p.
Kumar S. Neuroprotective role of Cassia tora and Caesalpinia crista with special emphasis on Alzheimer’s disease [PhD thesis]. Department of Biochemistry, Mangalore University; 2019.
Chethana K, Sasidhar B, Naika M, et al. Phytochemical composition of Caesalpinia crista extract as potential source for inhibiting cholinesterase and β-amyloid aggregation: Significance to Alzheimer’s disease. Asian Pacific Journal of Tropical Biomedicine. 2018; 8(10): 500-12p.
Nathala E, Dhingra S. biological effects of Caesalpinia crista seed extracts on Helicoverpa armigera (Lepidoptera: Noctuidae) and its predator, Coccinella septumpunctata (Coleoptera: Coccinellidae). J Asia-Pacific Entomology. 2006; 9(2): 159-64p.
Sarkar R, Hazra B, Mandal N. Hepatoprotective potential of Caesalpinia crista against iron-overload-induced liver toxicity in mice. Evidence-Based Complementary and Alternative Medicine. 2012; 2012: 1-9p.
Gupta N, Chauhan P, Nayeem M, et al. Hepatoprotective effect of Caesalpinia crista Linn. against CCl4 and paracetamol induced hepatotoxicity in albino rats. African J of Pharmacy and Pharmacology. 2014; 8(18): 485-91p.
Gaurav S, Govindasamy J. Hepatoprotective potential of ethanolic leaf extract of plant Piper attenuatum B. Ham and Caesalpinia crista Linn. Intern J Drug Devel and Res. 2021; 13(3): 1-5p.
Sharma R, Sharma K. Cardio protective effect of Caesalpinia crista Linn. on Isoproterenol induced myocardial necrosis in Rats. Inter J Pharma and Sci. 2013; 3(1): 119-30p.
Kshirsagar S, Sakarkar D , Deshpande S. Evaluation of acute and sub-acute toxicity of ethanolic extract of seed kernels of Caesalpinia crista (Linn.) in albino mice. IJPSR, 2012; 3(4): 1164-8p.
Jain SK, Chitme H, Chandra R. Antimalarial activity of a new herbal formulation. Ind J Pharmac Sci. 2005; 2:101-3p.
DOI: https://doi.org/10.37591/rrjob.v11i3.3559
Refbacks
- There are currently no refbacks.
Copyright (c) 2023 Research & Reviews: Journal of Botany