Development of a New Kisspeptin Based Method of Ovulation Synchronization for Crossbred Dairy Heifers

Authors

  • M Mondal
  • KK Baruah
  • M Karunakaran
  • MK Ghosh
  • TK Dutta

DOI:

https://doi.org/10.37591/rrjodst.v4i3.435

Abstract

The aim of the present study was to develop a new method of synchronization of estrus/ovulation for crossbred cows based on kisspeptin, a potent secretagogue of GnRH. For the purpose, a total of 108 estrous cycles were studied in cyclic heifers. The animals divided equally in to two groups were treated either with ovsynch protocol of estrus synchronization (group-I; GnRH: day 0; PGF2α: day 7 and GnRH: day 9) or with a new method of synchronization based on kisspeptin (group-II; kisspeptin: day 0; PGF2α: day 7 and kisspeptin: day 9). Heifers were monitored regularly with transrectal ultrasonography for follicular dynamics and occurrence of ovulation. It was found that the kisspeptin based protocol induced better growth of follicles than ovsynch one. Ovulation rate was significantly higher (P<0.05) in the animals of group-II than group-I. As revealed through ultrasonography as well as plasma progesterone profiles, the process of luteolysis starts early even before PGF2α injection in kisspeptin based protocol than ovsynch. In conclusion, we developed a new method of synchronization of estrus/ovulation based on kisspeptin in bovine species for the first time. The newly developed method is found to be better than the conventional ovsynch method in terms of percent ovulation in the treated animals.

 

Keywords: Estrus, ovulation, synchronization, kisspeptin, metastin, bovine

Cite this Article

MondalM,Baruah KK, Karunakaran M et al. Development of a New Kisspeptin Based Method of Ovulation Synchronization for Crossbred Dairy Heifers. Research & Reviews: Journal of Dairy Science and Technology. 2015; 4(3):12–16p.

Downloads

Published

2018-04-20

Issue

Vol. 4 No. 3 (2015)

Section

Research Article

License

Declaration and Copyright Transfer Form

(to be completed by authors)

I/ We, the undersigned author(s) of the submitted manuscript, hereby declare, that the above manuscript which is submitted for publication in the STM Journals(s), is not published already in part or whole (except in the form of abstract) in any journal or magazine for private or public circulation, and, is not under consideration of publication elsewhere.

  • I/We will not withdraw the manuscript after 1 week of submission as I have read the Author Guidelines and will adhere to the guidelines.
  • I/We Author(s ) have niether given nor will give this manuscript elsewhere for publishing after submitting in STM Journal(s).
  • I/ We have read the original version of the manuscript and am/ are responsible for the thought contents embodied in it. The work dealt in the manuscript is my/ our own, and my/ our individual contribution to this work is significant enough to qualify for authorship.
  •  I/We also agree to the authorship of the article in the following order:

Author’s name                                    

 

1. ________________

2. ________________

3. ________________

4. ________________

 

We  Author(s) tick this box and would request you to consider it as our signature as we agree to the terms of this Copyright Notice, which will apply to this submission if and when it is published by this journal.