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Study of Immune Response and Phototherapeutics of Viral Disease

JEFFERSON LORENÇONI MORAIS, Vikas Mahendra Sharma

Abstract


How much the world has been facing the pandemic caused by COVID-19, which brought great despair around the world? As we know, this virus has had several negative effects, such as social distance, closing companies, schools and distance between families. Especially with great effects on people in the risk group who have chronic diseases like asthma, diabetes, hypertension, heart disease, cancer and people who do not have a very good and strong immune system that can fight this terrible virus. 'Immunity' or known as natural defense, which helps to fight external agents that harm our organism. This new coronavirus has symptomatic and asymptomatic characteristics in its victims, due to the presentation of the immune status of its host. In this article, we mention how immunity works against this deadly virus. We also emphasize that it is possible to create a good and healthy immune system, with demonstration of an adequate diet, good physical exercise and meditation. We also present herbs / plants and vitamins that can help the immune system in curative treatment, presenting its side effects, its biodegradation and very easily obtained in nature. Our future scope is to study the molecular structure of phytonutrients or phytochemicals and their interaction with the defense system in the human body.


Keywords


Immunity, Prevention, Phytochemicals, ACE 2

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References


Daniel Wrapp, Nianshuang Wang, Kizzmekia S. Corbett, Jory A. Goldsmith, Ching-Lin Hsieh, Olubukola Abiona, Barney S. Graham, Jason S. McLellan. Published the structure Cryo-EM doPico 2019-nCoV in the formation of preference. Science 367, 1260–1263 (2020).

Zunyou Wu, MD, PhD, Jennifer M. McGoogan, PhD, published resources and important lessons from the Coronavirus Outbreak 2019 (COVID-19) China Outbreak Summary of a case report 72314 from the JAMA Chinese Center for Disease Control, published online on February 24, 2020.

Jan Dansen AH, Epstein M, Batlle D. Renin-angiotensin system blockers and the Covid-19 pandemic. Hypertension. 2020.

Matthew Zirui Tay, Chek Meng Poh, Laurent Rénia, Paul A. Mac Ary and Lisa F.P. Ng. The trinity of COVID-19: immunity, inflammation and intervention.

Fehr A.R. Perlman S. Coronaviruses: an overview of their replication and pathogenesis. Methods. Mol. Biol. 1282, 1–23 (2015).

Coronaviridae Study Group of the International Committee on Taxonomy of Viruses. The species severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2. Nat. Microbiol. 5, 536–544 (2020).

Zhou P. et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature 579,270–273 (2020).

Guan WJ, et al. Clinical characteristics of coronavirus disease 2019 in China. N. Engl. J. Med. https://doi.org/10. 1056/NEJMoa2002032 (2020).

Pung R. et al. Investigation of three clusters of COVID-19 in Singapore:implications for surveillance and response measures. Lancet 395, 1039– 1046 (2020).

Lauer SA et al. The incubation period of coronavirus disease 2019 (COVID-19) from publicly reported confirmed cases: estimation and application. Ann. Intern. Med. https://doi.org/10.7326/m20–0504(2020)

Li Q et al. Early transmission dynamics in Wuhan, China, of Novel Coronavirus-infected pneumonia. N. Engl. J. Med. 382, 1199–1207 (2020).

Wilson de Melo Cruvinel, Danilo Mesquita Júnior, Júlio Antônio Pereira Araújo, Tânia Tieko Takao Catelan, Alexandre Wagner Silva de Souza, Neusa Pereira da Silva and Luís Eduardo Coelho Andrade. Published immune system—Part I Fundamentals of innate immunity, with an emphasis on the molecular properties and cellular mechanisms of the inflammatory response.

Bras J Rheumatol 2010; 50 (4): 434–61.07. Yufang Shi, Ying Wang, Changshun Shao, Jianan Huang, Jianhe Gan, Xiaoping Huang, Enrico Bucci, Mauro Piacentini, Giuseppe Ippolito, Gerry Melino. COVID-19 infection published: perspectives on immune responses. https://www.nature.com /articles/s41418–020–0530–308.

Kaziyama, VM; Fernandes, MJB; Simoni, IC Publication of antiviral activity of commercially available herbal extracts against porcine and bovine herpes viruses. Http://doi.org/10.1590/S1516–05722012000300015

Gene: ACE2, Angiotensin Converting Enzyme 1, 2. National Center for Biotechnological Information (NCBI).US National Library of Medicine. 2020–02–28.

Supinda Bunyavanich, MD, MPH and Do, PhD. Published the nasal gene expression of angiotensin converting enzyme 2 in children and adults. DOI: 10.1001/jama.2020.8707

Reeves GEM, Boyle MJ, Bonfied J, Dobson P, Loewenthal M. Impact of hydroxychloroquine on chronic urticaria: chronic autoimmune urticaria study and evaluation. Intern Med J. 2004;34:182–6.

Zhou D, Dai AM, Tong Q. Covid-19: a recommendation to examine the effect of hydroxychloroquine in preventing infection and progression. Antimicrobial Chemotherapy. 2020.

Vaduganathan M, Vardeny O, Michel T, McMurray JJV, Pfeffer MA, Solomon SD. Renin angiotensin aldosterone system inhibitor in patients with Covid-19. N England J Med. 2020.

Chan JF et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet. 395, 514–523 (2020).

Huang C et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 395, 497–506 (2020). This prospective study is the earliest to include an analysis of cytokine levels in severe and mild COVID-19, showing the presence of a cytokine storm analogous to that found for SARS-CoV infection.

Chen G. et al. Clinical and immunologic features of severe and moderate coronavirus disease 2019.J. Clin. Invest. https://doi.org/10.1172/jci137244(2020).

Liu Y. et al. Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury. Sci. China Life Sci. 63, 364–374 (2020).

Chen N. et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 395, 507–513 (2020).

Phan LT et al. Importation and human-to-human transmission of a novel coronavirus in Vietnam. N. Engl. J. Med. 382, 872–874 (2020).

Preeti Sharma, Pradeep Kumar, Rachna Sharma, Gaurav Gupta, Anuj Chaudhry Department of Biochemistry, Santosh Medical College and Hospital, Santosh University, Ghaziabad, Uttar Pradesh, India, 2 Department of Biochemistry, TSM Medical College and Hospital, Lucknow, Uttar Pradesh, India, 3Department of Nano, Medical and Polymer Materials, Yeungnam University, Gyeongsan, South Korea. DOI 10.5455/njppp.2017.7.0203808032017.

Ramalingum N, Mahomoodally MF. The therapeutic potential of medicinal foods. Adv Pharmacol Sci. 2014;2014:354264.

Dias DA, Urban S, Roessner U. A historical overview of natural products in drug discovery. Metabolites. 2012;2(2):303–36.

Spelman K, Burns J, Nichols D, Winters N, Ottersberg S, Tenborg M. Modulation of cytokine expression by traditional medicines: A review of herbal immunomodulators. Altern Med Rev. 2006;11(2):128–50.

Role of herbal medicine in boosting immune system. Immunopathol Persa. 2015;1(1):e01.

Akanksha Shrivastava: Poshan-news-covid-19-herbs-that-strenthen-you immunesystem/350819)

Singh UP, Prithiviraj B, Sarma BK, Singh M, Ray AB. Role of garlic (Allium

sativum L.) in human and plant diseases. Indian J Exp Biol. 2001;39(4):310–22.

Liu P, Chen D, Shi J. Chemical constituents, biological activity and agricultural cultivation of Aloe vera: A review. Asian J Chem. 2013;25(12):6477.

Contributors to Wikimedia projects (2007). species of plant. [online] Wikipedia.org. Available at: https://en.m.wikipedia.org/wiki/Tinospora_cordifolia [Accessed August 2020]


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