Formulation Boswellia serrata and Commiphora mukul Extract Gel for Topical Inflammation

Abstract

Inflammation and rheumatism remain serious health problems in the present era. In the present attempt, the authors developed anti-inflammatory gel which gives benefit of faster permeation for quicker action. This anti-inflammatory gel is very useful for the arthritis patients. For the formulation purpose Boswellia serrata (Shallaki) and Commiphora mukul (Guggul) were selected because very less work has been done on these plants and for synergistic effect known of herbal extracts namely Boswellic acid and Guggulsterone were used. The literature survey and preliminary phytochemical screening revealed that triterpenoids are the secondary metabolites present in active extracts and isolated compounds of all these herbal drugs which may be responsible for anti-inflammatory activity. On the basis of experimentation work and results, the authors can say this formulation of Boswellic acid and Guggulsterone possesses well anti-inflammatory synergistic action along with good antibacterial activity. In future, it will be possible to isolate various classes of secondary metabolites by applying different separation techniques such as preparative TLC, column chromatography and screening of anti-inflammatory and antimicrobial activity of the major phyto-constituents from extracts. So, in future isolation of such active principles in pure form and its development can lead to new potent anti-inflammatory and antimicrobial compounds. 

Keywords: Anti-inflammatory, Boswellia serrata, Commiphora mukul, Secondary metabolites

Cite this Article

Pardhi Dinesh, Vyawahare Namrata, Dol Hemalata, et al. Formulation Boswellia serrata and Commiphora mukul Extract Gel for Topical Inflammation. Research and Reviews: Journal of Herbal Science (RRJoHS). 2015; 4(2): 1–8p.