EVALUATION OF ANTIBACTERIAL POTENTIAL OF BARLERIA NITIDA NEES

Abstract

Abstract

Plants are gift of nature and used as medicine in traditional medicinal system since thousands of years ago. In this study, the antibacterial potential of various solvent extracts of aerial and underground parts of Barleria nitida Nees was evaluated against eight selected human pathogens. The pathogens used in this study were Escherichia coli, Klebsiella pneumoniae, Enterobacter aerogenes, Pseudomonas aeruginosa, Proteus mirabilis, Enterococcus faecalis, Bacillus cereus and Staphylococcus aureus. The shade dried plant powder was successively extracted with petroleum ether, benzene, chloroform and ethanol based on the increasing polarity. Distilled water extract was prepared separately. Antibacterial potential of the plant extraction was done by disc diffusion method. The aerial and underground part of Barleria nitida showed maximum zone of inhibition in ethanol extract against Enterobacter aerogenes, Proteus mirabilis and Enterococcus faecalis. The result revealed that the plant has the potent antibacterial activity which can be used to prepare the medicine in pharmaceutical industries after the isolation of pure compound.

Keywords: Medicinal plants, Barleria nitida Nees, antibacterial activity screening

Cite this Article

R. Pramely, T. Leon Stephan Raj, L. Henry Joseph. Evaluation of Antibacterial Potential of Barleria nitida Nees. Research & Reviews: Journal of Herbal Science. 2018; 7(2): 1–3p.