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Boswellia serrata: A Review on its Phytochemical and Therapeutic Potential

Juveriya Naaz, Mariyam Roqaiya, K.M. Hina Fatima, Ziya ul Haq, Azhar Hasan Khan


Kundur or Boswellia serrata belongs to the genus Boswellia of Burseraceae family. It is usually found in Oman and Yaman, its effectiveness persists for 20 years. Its bark and gum are used for medicinal properties but Boswellia are well-known for producing a gum resin that is known as olibanum or frankincense. Gum-resin comprises triterpenes of oleanane, ursane and euphane series. The major chemical constituents reported for anti-inflammatory, antiproliferative and anticancer activities apart from this study shows multiple pharmacological properties like Antibacterial activity, Anticonvulsant effect, Anti-hyperlipidemic effect, Anti-diabetic effect, Antidepressant Activity, Analgesic properties Antiulcer Activity Antioxidant, Neurotoxicity. Clinical trials regarding this drug are also reported. Gum is a most important part of this plant as it has pretty much astringent property. Several human and animal studies reported but further in vivo and in vitro study is needed to explore its quality for further management.


Kundur, Boswellia serrata, gum, pharmacological properties, phytochemical properties, anti-inflammatory

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Ahmed HH, Abd-Rabou AA, Hassan AZ, Kotob SE. Phytochemical Analysis and Anticancer Investigation of Boswellia Serrata Bioactive Constituents In Vitro. Asian Pacific Journal of Cancer Prevention.2015; 16: 7179-7188.

Upaganlawar A, Balu Ghule B. Pharmacological Activities of Boswellia serrata Roxb. - Mini Review. Ethnobotanical Leaflets. 2009; 13: 766-74.

Sharma A, Chhikara S, Ghodekar SN, Bhatia S, Kharya MD, Gajbhiye V, et al. Phytochemical and Pharmacological investigations on Boswellia serrata. Pharmacognosy Review. 2009; 3(5): 206-215.

Khare CP. Indian Medicinal Plants. New York: Springer Science Business Media; 2007: 98, 533.

Rajput AP, Patil SY. Boswellia Serrata Roxb. A Boon of Nature in the World of Medicines: A Review. European Journal of Pharmaceutical and Medical Research. 2015; 2(7): 384-390.

Ibn baitar. Jamiul mufradat al Advia wa Aghzia. Vol 4. Delhi: CCRUM; 2003: 201-206, 316-320.

Ghani HN. Khazainul Advia. 2nd Edition. New Delhi: Idarae Kitab ul Shifa; 2008: 388,389,811,812,1069,1070,1229,1230.

Prajapathi ND, Purohit SS, Sharma AK, Kumar T. A Handbook of Medicinal Plants; Agrobios India; 2003: 96,164,165.

Rushd MWA. Kitabul Kulliyat . New Delhi: CCRUM; 1987: 274,292.

Razi AMZ. Kital-al-Hawi Vol-10. New Delhi: CCRUM; 2002: 193-195.

Mashhadi FF, Salimi S, Forouzandeh F, Naghsh N. Comparison of Anticancer Activity of Hydroalcoholic Extracts of Curcuma longa L., Peganum harmala L., and Boswellia serrata on HeLa cells. Jundishapur Journal Natural Pharmaceutical Products. 2017; 12(2): e37336.

Bhushan S, Kumar A, Malik F, Andotra SS, Sethi VK, Kaur IP, et al. A triterpenediol from Boswellia serrata induces apoptosis through both the intrinsic and extrinsic apoptotic pathways in human leukemia HL-60 cells. Apoptosis. 2007; 12: 1911-1926.

Khan MA, Singh M, Khan MS, Najmi AK, Ahmad S. Caspase Mediated Synergistic Effect of Boswellia serrata Extract in Combination with Doxorubicin against Human Hepatocellular Carcinoma. Hindawi Publishing Corporation Journal of Biomedicine and Biotechnology. 2014; 3: 11.

Yuan G, Wahlqvist ML, He G, Yang M, Li D. Natural products and anti-inflammatory activity. Asia Pacific Journal of Clinical Nutrition. 2006; 15(2): 143-152.

Siddiqui MZ. Boswellia serrata, a potential anti-inflammatory agent: An overview. Indian journal of pharmaceutical sciences. 2011; 73(3): 255-256.

Yuan G, Wahlqvist M L, Guoqing He G, Yang M, Li D. Natural products and anti-inflammatory activity. Asia Pac J Clin Nutr. 2006; 15 (2): 143-152.

Maraghehpour B, Khayamzadeh M, Najafi S, Kharazifard M. Traditionally used herbal medicines with antibacterial effect on Aggegatibacter actinomycetemcomitans: Boswellia serrata and Nigella sativa. Journal of Indian Society of Periodontology.2016;20(6): 603-607.

Aman M, Rai R, Samaga PV. Antimicrobial and Phytochemical Screening of Boswellia serrata roxb., Rhus mysorensis Heyne, strychnos potatorum Linn. F and Schefflera stellate Gaertn. Medicinal and aromatic palnt science and biotechnology. 2010; 4(4): 69-72.

Ismail SM, Aluru S, Sambasivarao KRS, Matcha B. Antimicrobial activity of frankincense of Boswellia serrata. International Journal of Current Microbiology and Applied Sciences. 2014; 3(10): 1095-1101.

Ziyaurrahman AR, Patel J. Anticonvulsant effect of Boswellia serrata by modulation of endogenous biomarkers. Der Pharmacia Lettre. 2012; 4(4): 1308-1326.

Ahangarpour A, Heidari H, Fatemeh RAA, Pakmehr M, Shahbazian H, Ahmadi I, et al. Effect of Boswellia serrata supplementation on blood lipid, hepatic enzymes and fructosamine levels in type2 diabetic patients. Journal of Diabetes & Metabolic Disorders. 2014; 13(29): 1-5.

Shehata AM, Quintanilla-Fend L, SabrinaBettio, Singh CB, Ammon HPT. Prevention of multiple low-dose streptozotocin (MLD-STZ) diabetes in mice by an extract from gum resin of Boswellia serrata (BE). Phytomedicine Elsevier. 2011;18(12): 1037-1044.

Adake P, Chandrashekar R, Rao SN. Preclinical evaluation of antidepressant activity of Boswellia serrata by Tail Suspension Test. The Pharma Innovation – Journal.2013;2(5): 13-18.

Bolognesi G, Belcaro G, Feragalli B, Cornell U, Cotellese RUHS, Dugall M.Movardol (N-acetylglucosamine,Boswellia serrata, ginger) supplementation in the management of knee osteoarthritis: preliminary results from a 6-month registry study. European Review for Medical and Pharmacological Sciences. 2016; 20: 5198-5204.

Umar S, Umar K, Golamsarwar AHM, Khan A, Ahmad N, Ahmad S, et al. Boswellia serrata extract attenuates inflammatory mediators and oxidative stress in collagen induced arthritis. Phytomedicine Elsevier. 2014;21(6): 847-856.

Krieglstein CF, Anthoni C, Rijcken EJM, Laukötter M, Spiegel HU, Boden SE, et al. Acetyl-11-keto-boswellic acid, a constituent of a herbal medicine from Boswellia serrata resin, attenuates experimental ileitis. International Journal Colorectal Disease. 2001; 16: 88-95.

Lampl C, Haider B, Schweiger C. Long-term efficacy of Boswellia serrata in 4 patients with chronic cluster headache. The Journal of Headache and Pain. 2013; 14(1):37.

Prabhavathi K, Chandra USJ, Soanker R, Rani PU. A randomized, double blind, placebo controlled, cross over study to evaluate the analgesic activity of Boswellia serrata in healthy volunteers using mechanical pain model. Indian Journal of Pharmacology. 2014;46(5): 475-479.

Hartmann RM, Martins MIM, Tieppo J, Fillmann HS, Marroni NP. Effect of Boswellia serrata on Antioxidant Status in an Experimental Model of Colitis Rats Induced by Acetic Acid. Digestive Diseases and Sciences- Springers. 2012; 57: 2038-2044. DOI 10.1007/s10620-012-2134-3.

Kokkiripati PK, Bhakshu LM, Marri S, Padmasree, Row AT, Raghavendra AS, et al. Gum resin of Boswellia serrata human monolytic (THP-1) cell activation and platelet aggregation. Journal of Ethnopharmacology-Elsevier. 2011; 137(1): 893-901.

Beghelli D, Isani G, Roncada P, Andreani G, Bistoni O, Bertocchi M, Lupidi G. Antioxidant and Ex Vivo Immune System Regulatory Properties of Boswellia serrate Extracts. Hindawi Oxidative Medicine and Cellular Longevity. 2017: 10.

Zeeyauddin K, Narsu ML, Abid M, Ibrahim M. Evaluation of antiulcer activity of Boswellia serrata bark extracts using aspirin induced ulcer model in albino rats. Journal of Medical Allied Sciences. 2011; 1(1): 14 -20.

Kazmi1 S, Kafami L, Ebrahimi A, Jameie B, Joghataei MT. The Effects of Boswellia Resin Extract on Dopaminergic Cell line, SK-N-SH, against MPP+-Induced Neurotoxicity. Basic and Clinical Neuroscience. 2011; 3(1): 16-21.

Sharifabad MH, Ardakani RK, Sharifabad AH. Beneficial effect of Boswellia serrata gum resin on spatial learning and the dendritic tree of dentate gyrus granule cells in aged rats. Avicenna Journal Of Phytomedicine.2016; 6(2): 189-197.

Jalili C, Salahshoor MR, Moradi S, Pourmotabbed A, Motaghi M. The Therapeutic Effect of the Aqueous Extract of Boswellia Serrata on the Learning Deficit in Kindled Rats. International Journal of Preventive Medicine,.2014; 5(5): 563-568.

Kizhakkedath R. Clinical evaluation of a formulation containing Curcuma longa and Boswellia serrata extracts in the management of knee osteoarthritis. Molecular Medicine Reports. 2008; 8: 1542-1548 DOI: 10.3892/mmr.2013.1661.

Kimmatkar N, Thawani V, Hingorani L, Khiyani R. Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee – A randomized double blind placebo controlled trial. Phytomedicine journal- Elsevier.2003; 10(1): 3-7.

Sontakke S, Thawani V, Pimpalkhute, Kabre S, Bhabulkar S, Hingorani L. Open, Randomized, controlled clinical trial of Boswellia seratta extract as compared to valdecoxib in osteoarthritis of knee. Indian Journal of Pharmacology 2007; 39(1): 27-29.

Fatima S, Ahmad T, Shahid M, Sofia G. Comparative Study of Kundur (Boswellia serrata) and Tareeq (Diaphoresis) in the Management of Samne Mufrit (Obesity): A Randomised Clinical Trial. International Journal of Health Sciences and Research. 2017; 7(10): 186-197.

Madisch A, Miehlke S, Eichele O, Mrwa J, Bethke B, Kuhlisch E, et al. Boswellia serrata extract for the treatment of collagenous colitis. A double-blind, randomized, placebo controlled, multicenter trial. International Journal of Colorectal Disease Springer. 2007; 22: 14445-1451.


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