Open Access Open Access  Restricted Access Subscription or Fee Access

A Review on Ethnobotanical, Therapeutic, and Pharmaceutical Uses of Medicinal Plant—Hibiscus Sabdariffa

Puneet Gulati

Abstract


Over 300 types of hibiscus have been discovered overall which are essentially spoken to the Malvaceae family. Hibiscus sabdariffa was first found in the zones of Sudan. It is generally known as “Roselle” and “Karkade”. The principal focal point of this plant is its beefy sepals which are economically truly important and expanded its quality. This plant is utilized to make plenty of food things, for example, jams, confections, sauces, and go about as flavonoids and shading specialists just as used in numerous sorts of beverages. Hibiscus sabdariffa has a lot more uses like developed as fancy plants, having restorative characteristics because of the presence of nutrients, proteins, greasy substances, minerals, wholesome segments, and acids. The plant has incredible arrangement against cancer, hostile to hypertension, stoutness also, hostile to hyperlipidemic and so forth. Rather than this, hibiscus is burned through for various purposes, for example, natural beverages in the types of drinks, food, and hallucinogenic (a medication causing fantasy) admissions to keep from different diseases. Concentrate portrays against hypertensive, cell reinforcement, hostile to pyretic, diuretic impact, hostile to diabetic, and against bacterial properties. Hibiscus sabdariffa is one of the celebrated harvests which are acquiring the notoriety to handle numerous genuine issues. The concentrate of roselle comprises saponins, glycosides, alkaloids, and flavonoids. It speaks to antibacterial exercises against Bacillus stearothermophilus, Clostridium sporogenes, Klebsiella pneumonia, Staphylococcus aureus, Escherichia coli, and Bacillus cereus.


Keywords


Ethnobotanical, hibiscus, pharmaceutical, therapeutic, traditional

Full Text:

PDF

References


Alemayehu, K. and Desalegn, T., 2016. Antibiotic effects of Argemone mexicana (Papaveraceae) against field crops and pathogens causing mastitis in Dairy Cattle in three districts of Amhara Region, Ethiopia. Journal of Advances in Biology & Biotechnology, pp.1-9.

Komarov VL. Flora of the USSR. Israel program for scientific translation. An immense (25 or more large volumes) and not yet completed translation of the Russian flora. Full of information on plant uses and habitats but heavy going for casual readers. 1968.

Clydesdale FM, Main JH, Francis FJ. Roselle (Hibiscus sabdariffa L.) anthocyanins as colorants for beverages and gelatin desserts. Journal of Food Protection. 1979; 42(3): 204–207.

Al-Wandawi H, Al-Shaikhly K, Abdul-Rahman M. Roselle seeds: a new protein source. Journal of Agricultural and Food Chemistry. 1984; 32(3): 510–512.

Elamin KM, Hassan HE, Abadalla HO, Arabi OH, Tameem Eldar AA. Effect of feeding crushed Roselle seed (Hibiscus sabdariffa L.) on carcass characteristics of Sudan desert sheep. Asian Journal of Animal Science. 2012; 6(5): 240–248.

Mukhtar MA. The effect of feeding rosella (Hibiscus sabdariffa) seed on broiler chick’s performance. Research Journal of Animal and Veterinary Sciences. 2007; 2: 21–23.

Franz M, Franz G. Hibiscus sabdariffa. Phytotherapy. 1988; 9(2): 63.

Mckay DL, Chen CYO, Saltzman E, Blumberg JB. Hibiscus sabdariffa L. Tea (Tisane) lowers blood pressure in prehypertensive and mildy hypertensive adults. J. Nvtr. 2010; 140: 298–303.

Herrera-Arellano A, Miranda-Sanchez J, Avila-Castro P, Herrera-Alverez S, Jimenez-Ferrer JE, Zamilpa A, Roman-Roman R, Ponce-Monter H, Tortoriello J. Clinical effects produced by a standardized herbal medicinal product of Hibiscus sabdariffa on patients with hypertension. A randomized, double-blind, lisinopril-controlled clinical trial. Planta Med. 2007; 73(1): 6–12.

Herrera-Arellano A, Flores-Romero S, Chavez-Soto MA, Tortoriello J. Effectiveness and tolerability of a standardized extract from Hibiscus sabdariffa in patients with mild to moderate hypertension: a controlled and randomized clinical trial. Phytomedicine. 2004; 11(5): 375–382.

Gurrola-Diaz CM, Garcia-Lopez PM, Sanchez-Enriquez S, Troyo Sanroman R, AndradeGonzalez I, Gomez Leyva JF. Effects of Hibiscus sabdariffa extract powder and preventive treatment (diet) on the lipid profiles of patients with metabolic syndrome (MeSy). Phytomedicine. 2010; 17(7): 500–505.

Mozaffari-Khosravi H, Jalali-Khanabadi B, Afkhami-Ardekani M, et al. The effects of sour tea (Hibiscus sabdariffa) on hypertension in patients with type II diabetes. J Human Hypertension. 2009; 23(1): 48–54.

Jonader M, Bastide J, Bastide P, Boyer B, Carnar AP, Lamaison JL. In vitro enzyme inhibitory and in vivo cardioprotective activities of hibiscus (Hibiscus sabdariffa L). Journal de Pharmacie de Belgique. 1990; 45(2): 120–124.

Obeituna PCM, Owlabi OA, Adegunloye BJ, Obiefuna IP, Sofola OA. The petal extract of Hibiscus sabdariffa produces relaxation of isolated rat aorta. Pharmaceutical Biology. 1994; 32 (1): 69–74.

Adegunloye BJ, Ominiyi JO, Owolobi OA, Ajagbonna OP, Safola OA, Coker HA. Mechanisms of the blood pressure lowering effect of the calyx extract of Hibiscus sabdariffa in rats. African Journal of Medicines and Medical Sciences. 1996; 25(3): 235–238.

Ajay M, Chai HJ, Mustafa AM, Gilani AH, Mustafa MR. Mechanisms of the anti-hypertensive effect of Hibiscus sabdariffa L. calyces. Journal of Ethnopharmacology. 2007; 109(3): 388–393.

Inuwa I, Ali BH, Al-Lawati I, Beegam S, Ziada A, Bluenden G. Long-term ingestion of Hibiscus sabdariffa calyx extract enhances myocardial capillarization in the spontaneously hypertensive rat. Experimental Biology and Medicine (Maywood). 2012; 237(5): 563–569.

Mojimininiyi FBO, Dikko M, Muhammad BY, Ojbor PD, Ajagboma OP, Okolo RU, et al. Antihypertensive effect of an aqueous extract of the calyx of Hibiscus sabdariffa. Fitoterapia. 2007; 78(4): 292–297.

Oxyenekwe PC, Ajani EO, Ameh DA, Gamaniel KS. Antihypertensive effect of roselle calyx infusion in spontaneously hypertensive rats and a comparison of its toxicity with that in wistar rats. Cell Biochemistry and Function. 1999; 17(3): 199–206.

Shehata AM, EI Menoufy GA. Comparative studies on the possible therapeutic effect of a natural remedy and hypertensive drugs on hypertension-induced gonadal dysfunction in male rats. Journal of Drug Research of Egypt. 2008; 29(1): 1–7.

Mojiminiyi FBO, Adegunloye BJ, Egbeniyi YA, Okolo RU. An investigation of the diuretic effect of an aqueous extract of the petals of Hibiscus sabdariffa. African Journal of Medicine and Medical Sciences. 2000; 2(1): 77–80.

Yamamoto J, Yamada K, Naemura A, Yamashita T, Arai R. Testing various herbs for antithrombotic effect. Nutrition. 2005; 21(5): 580–587.

Mounnissamy VM, Kavimani S, Gunasegaran R. Antibacterial activity of gossypetin isolated from Hibiscus sabdariffa. The Antiseptic. 2002; 99(3): 81–82.

Joshi H, Parle M. Nootropic activity of calyces of Hibiscus sabdariffa. Iranian J Pharmacol Therapeutics. 2006; 5(1): 15–20.

Liu KS, Tsao SM, Yin MC. In vitro antibacterial activity of roselle calyx and protocatechuic acid. Phytotherapy Research. 2005; 19(11): 942–945.

Aflabi OC, Ogunsola FT, Coker AO. Susceptibility of cariogenic Streptococcus mutans to extracts of Garcinia kola, Hibiscus sabdariffa, and Solanum americanum. West African Journal of Medicine. 2008; 27(4): 230–233.

Nwaiwu NE, Mshelia F, Raufu IA. Antimicrobial activities of crude extract of Moringa oleifera, Hibiscus sabdariffa, and Hibiscus esculentus seeds against some enterobacteria. Journal of Applied Phytotechnology in Environmental Sanitation. 2012; 1(1): 11–16.

Olalye MT, Rocha JBT. Commonly used tropical medicinal plants exhibit distinct in vitro antioxidant activities against hepatotoxins in rat liver. Experimental and Toxicologic Pathology. 2007; 58(6): 433–438.

Farombi EO, Fakoya A. Free radical scavenging and antigenotoxic activities of natural phenolic compounds in dried flowers of Hibiscus sabdariffa L. Mol Nutr Food Res. 2005; 49(12): 1120– 1128.

Christian KR, Nair MG, Jackson JC. Antioxidant and cyclooxygenase inhibitory activities of sorrel (Hibiscus sabdariffa). J Food Comp Anal. 2006; 19(8): 778–783.

Duh PD, Yen GC. Antioxidative activity of three herbal water extracts. Food Chemistry. 1997; 60(4): 639–645.

Hirunpanich V, Utaipat A, Morales NP, Bunyaphatsara N, Sato H, Herunsalee A, et al. Antioxidant effects of aqueous extracts from dried calyx of Hibiscus sabdariffa Linn. (Roselle) in vitro using rat low-density lipoprotein (LDL). Biological & Pharmaceutical Bulletin. 2005; 28(3): 481–484.

Mohd-Esa N, Hern FS, Ismail A, Yee CL. Antioxidant activity in different parts of roselle (Hibiscus Sabdariffa L.) extracts and potential exploitation of the seeds. Food Chemistry. 2010; 122(4): 1055–1060.

Sayago-Ayerdi SG, Arranz S, Serrano J, Goni I. Dietary fibre content and associated antioxidant compounds in Roselle flower beverage. Journal of Agricultural and Food Chemistry. 2007; 155(19): 7886–7890.

Steenkamp V, Fernandas AC, Van Rensburg CEJ. Antioxidant scavenging potential of South Africa export herbal teas. South African Journal of Botany. 2004; 70(4): 660–663.

Tseng TH, Kao ES, Chu CY, Chou FP, Lin Wu HW, Wang CJ. Protective effects of dried flower extracts of Hibiscus sabdariffa L. against oxidative stress in rat primary hepatocytes. Food and Chemical, Toxicology. 1997; 35(12): 1159–1164.

Mossalam HH, Aty OAAE, Morgan EN, Youssaf SMS, Mackawy AMH. Biochemical and ultrastructure studies of the antioxidant effect of aqueous extract of Hibiscus sabdariffa on the nephrotoxicity induced by organo-phosphorous pesticide (Malathion) on the adult albino rats. Life Science Journal. 2011; 8(4): 561–574.

Ustoh IF, Akpan EJ, Elim EO, Farombi EO. Antioxidant actions of dried flower extracts of Hibiscus sabdariffa L. Pakistan Journal of Nutrition. 2005; 4(3): 135–141.

Chen J, Wang C, Sheu J, Lin C, Lin H. Hibiscus sabdariffa leaf polyphenolic extract inhibits LDL oxidation and foam cell formation involving up-regulation of LXRα/ABCA 1 pathway. Food Chem. 2013; 141(1): 397–406.

Yang MY, Huang CN, Chan KC, Yang YS, Peng CH, Wang CJ. Mulberry leaf polyphenols possess antiatherogenesis effect via inhibiting LDL oxidation and foam cell formation. J. Agriculture Food Chemistry. 2011; 59(5): 1985–1995.

Chen CC, Hsu JD, Wang SF, Chrang HC, Yang MY, Kao ES, HOYO, Wang CJ. Hibiscus sabdariffa extract inhibit the development of atherosclerosis in cholesterol-fed rabbits. J. Agri. Food Chem. 2003; 51(18): 5472–5477.

Wang M, Cheng H, Li Y, Meng L, Zhao G, Mai K. Herbs of the genus Phyllanthus in the treatment of chronic hepatitis B: observation with three preparations from different geographical sites. J. Lab Clin Med. 1995; 126(4): 350–352.

Chang YC, Huang HP, Hsu JD, Yang SF, Wang CJ. Hibiscus anthocyanins rich extract-induced apoptotic cell death in human promyelocytic leukemia cells. Toxico. Appl. Pharmacol. 2005; 205(3): 201–212.

Tseng TH, Hsu JD, Lo MH, Chu CY, Chou FP, Huang CL, Wang CJ. Inhibitory effect of Hibiscus protocatechuic acid on tumor promotion in mouse skin. Cancer Lett. 1998; 126(2): 199– 207.

Tseng TH, Kao TW, Chu CY, Chau FP, Lin WL, Wang CJ. Induction of apoptosis by Hibiscus protocatechuic acid in human leukemia cells via reduction of retinoblastoma (RB) phosphorylation and Bcl-2-expression. Biochemical Pharmacolog. 2000; 60(3): 307–315.

Md Akim A, Lim CL, Asmah R, Zainul AZ. Antioxidant and anti-proliferative activities of roselle juice on CaOv-3, MCF-7, MDA-MB-231 and HeLa cancer cell lines. Afri J Pharma Pharmacol. 2011; 5(7): 957–965.

Lin HH, Chan KC, Sheu JY, Hsuan Wang CJH. Hibiscus sabdariffa leaf induces apoptosis of human prostate cancer cells in vitro and in vivo. Food Chemistry. 2012; 132(2): 880–891.

Balouiri M, Sadiki M, Ibnsouda SK. Methods for in vitro evaluating antimicrobial activity: a review. J. Pharmaceutical Analysis. 2016; 6(2): 71–79.

Fullerton M, Khatiwada J, Johnson JU, Davis S, Williams LL. Determination of antimicrobial activity of sorrel on E. coli O157: H7 isolated from food, veterinary, and clinical samples. J Med Food. 2011; 14(9): 950–956.

Olantunji LA, Adebayo JO, Oguntoye OB, Olantunde NO, Olantunji VA, Soladoye AO. Effects of aqueous extract of petals of red and green Hibiscus sabdariffa on plasma liquid and hematological variables in rats. Pharm. Biol. 2005; 43(5): 471–474.

Abbas M, Shirin M, Patricia K, Mohammad GK. The effect of Hibiscus sabdariffa on lipid profile, creatinine, and serum electrolytes: a randomized clinical trial. ISRN Gastroenterol. 2011: 1–4.

El-Adawy TA, Khalil AH. Characteristics of roselle seeds as a new source of protein and lipid. Journal of Agricultural and Food Chemistry. 1994; 42(9): 1896–1900.

Ahmad MU, Hussain SK, Ahmed I, Osman SM. Hibiscus sabdariffa seed oil: a re-investigation. Journal of the Science of Food and Agriculture. 1979; 30(4): 424–428.

Carvajal Zarrabal O, Waliszewski SM, Barradas-Dermitz DM, Orta-Flores Z, Hayward-Jones PM, Nolasco-Hipolito C, et al. The consumption of Hibiscus sabdariffa dried calyx ethanolic extract reduced lipid profile in rats. Plant Foods for Human Nutrition. 2005; 60(4): 153–159.

Chang YC, Huang KX, Huang AC, Ho YC, Wang CJ. Hibiscus anthocyanins-rich extract inhibited LDL oxidation and OxLDL-mediated macrophages apoptosis. Food and Chemical Toxicology. 2006; 44(7): 1015–1023.

El-saadany SS, Sitohy MZ, Labib SM, el-Massry RA. Biochemical dynamics and hypocholesterolemic action of Hibiscus sabdariffa (Karkade). Nahrung. 1991; 35(6): 567–576.

Gosain S, Ircchiaya R, Sharma PC, Thareja S, Kalra A, Deep A, et al. Hypolipidemic effect of ethanolic extract from the leaves of Hibiscus sabdariffa L. in hyperlipidemic rats. Acta Poloniae Pharmaceutica. 2010; 67(2): 179–184.

Hirunpanish V, Utipat A, Morales NP, Bunyapraphate N, Sato H, Herunsate A, et al. Hypocholesterolemic and antioxidant effects of aqueous extracts from the dried calyx of Hibiscus sabdariffa L. in hypercholestrolemic rats. Journal of Ethnopharmacology. 2006; 103(2): 252–260.

Ochani PC, D’ Mello P. Antioxidant and antihyperlipidemic activity of Hibiscus sabdariffa L. leaves and calyces extract in rats. Indian Journal of Experimental Biology. 2009; 47(4): 276– 282.

Yang MY, Peng CH, Chan KC, Yang YS, Huang CN, Wang CJ. The hypolipidemic effect of Hibiscus sabdariffa polyphenols via inhibiting lipogenesis and promoting hepatic lipid clearance. Journal of Agricultural and Food Chemistry. 2010; 58(2): 850–859.

Arvind M, Alka C. Hibiscus sabdariffa L: a rich source of secondary metabolites. International Journal of Pharmaceutical Sciences. 2011; 6(1): 83–87.

Okereke CN, Iroka FC, Chukwuma MO. Phytochemicals analysis and medicinal uses of Hibiscus sabdariffa. International Journal of Herbal Medicine. 2015; 2(6):16–19.

Nzikou JM, Bouanga-Kalou G, Matos L, Ganongo-Po FB, Mboungou-Mboussi PS, Moutoula. FE, et al. Characteristics and nutritional evaluation of seed oil from roselle in CongoBrazzaville. Current Research Journal of Biological Science. 2011; 3(2): 141–146.

Duke JA, Ayensu ES. Medicinal Plants of China. Book. Algonac, MI, USA, Strichzeichnungen. Reference Publ.; 1985.

Naturland. Organic Farming in the Tropics and Subtropics, Exemplary Description of 20 Crops. Germany: Naturland; 2000. pp. 1–22.

Dafallah AA, Al-Mustafa Z. Investigation of the anti-inflammatory activity of Acacia nilotica and Hibiscus sabdariffa. Am J Clin Med. 1996; 24(3–4): 263–269.

Adisakwattana S, Ruengsamran T, Kampa P, Sompong W. In vitro inhibitory effects of plantbased foods and their combination on intestinal α-glucosidase and pancreatic α-amylase. BMC Complementary and Alternative Medicine. 2012; 12(110).

Hansawasdi C, Kawabata J, Kasai T. Alpha amylase inhibitors from roselle tea. Bioscience, Biotechnology and Biochemistry. 2000; 64(5): 1041–1043.

Hansawasdi C, Kawabata J, Kasai T. Hibiscus acid is an inhibitor of starch digestion in caco-2 cell model system. Bioscience, Biotechnology and Biochemistry. 2001; 65(9): 2087–2089.

Penq CH, Chyau CC, Chan KC, et al. Hibiscus sabdariffa polyphenolic extract inhibits hyperglycaemia, hyperlipidemia, and glycation-oxidative stress while improving insulin resistance. Journal of Agricultural and Food Chemistry. 2011; 59(18): 9901–9909.

Lans CA. Ethnomedicines used in Trinidad and Tobago for urinary problems and diabetes mellitus. Journal of Ethobiology and Ethnomedicine. 2006; 2(1), pp.1-11.


Refbacks



Copyright (c) 2021 Research & Reviews: Journal of Ecology

eISSN: 2278–2230