Open Access Open Access  Restricted Access Subscription or Fee Access

The Development and Assessment of a Polyherbal Powder Formulation for the Treatment of Fungal Infections

Monam Mishra

Abstract


A poly-herbal powder drink was made in the current investigation utilizing a variety of conventional herbs that have been shown to have nutritional benefits. Tinosopra cordifolia, Cinnamomum verum, Zingiber officinale, Thymus sperpyllum, and menthe were chosen as the main components because they are commonly used in summer home routines and have a long history of providing a refreshing, cooling, and energizing effect. Following several tests, the final formulation's composition was chosen as the best mix based on the taste and physicochemical characteristics. The produced drink had an ideal pH level, which was in line with industry requirements, according to the physicochemica analysis. The drink scored highly on the colour, taste, flavour, and texture dimensions of the nine-point hedonic sensory evaluation. With a very nice flavour and possible health advantages, the new herbal beverage offers customers a practical and affordable choice. The current beverage has the potential to take the place of the artificial beverages now on the market.


Keywords


Polyherbal Powder Formulation, Antifungal Infection, Candida Albicans, Tinosopra Cordifolia, Antibacterial Activity; Phytochemical Analysis, Sensory Evaluation, Herbal Drugs

Full Text:

PDF

References


Ruhnke, Markus, and G. Maschmeyer. "Management of mycoses in patients with hematologic disease and cancer--review of the literature." European journal of medical research 7.5 (2002):227–235.

Meiller, Timothy F., et al. "A novel immune evasion strategy of Candida albicans: proteolytic cleavage of a salivary antimicrobial peptide." PloS one 4.4 (2009): e5039.

Schulze, Jürgen, and Ulrich Sonnenborn. "Yeasts in the gut: from commensals to infectious agents." Deutsches Ärzteblatt International 106.51–52 (2009): 837.

Dickey, Laura J., Michael D. Nailor, and Jack D. Sobel. "Guidelines for the treatment of bacterial vaginosis: focus on tinidazole." Therapeutics and Clinical Risk Management 5 (2009): 485.

Neeraja, P.V., and Elizabeth Margaret. "Amruthavalli: Tinospora cordifolia: Multipurpose rejuvenator." International Journal of Pharmaceutical, Chemical & Biological Sciences 3 (2013):233–41.

Pandey, M.U.K.E.S.H.W.A.R., et al. "Tinospora cordifolia: A climbing shrub in health care management." Int J Pharm Bio Sci 3.4 (2012): 612 628.

Spandana, U., et al. "A review on Tinospora cordifolia." International Journal of Current Pharmaceutical Review and Research 4.2 (2013): 61 68.

Agarwal, Pooja, and L. Nagesh. "Evaluation of the antimicrobial activity of various concentrations of Tulsi (Ocimum sanctum) extract against Streptococcus mutans: An in vitro study." Indian Journal of Dental Research 21.3 (2010): 357

Odds, Frank C. Candida and candidosis: a review and bibliography. Bailliere Tindall, 1988.

Soll, DAVID R., et al. "Multiple Candida strains in the course of a single systemic infection." Journal of Clinical Microbiology 26.8 (1988): 1448-1459.

Calderone, R.A., and C. Clancy. "Candida and candidiasis Washington." DC: American Society for Microbiology (2002).

Sexton, Jessica A., Victoria Brown, and Mark Johnston. "Regulation of sugar transport and metabolism by the Candida albicans Rgt1 transcriptional repressor." Yeast 24.10 (2007): 847–860.

Gordon, Morris A. "Rapid serological differentiation of Candida albicans from Candida stellatoidea." Journal of Investigative Dermatology 31.2 (1958): 123–125.

Gordon, Morris A. "Differentiation of yeasts by means of fluorescent antibody." Proceedings of the Society for Experimental Biology and Medicine 97.3 (1958): 694–698.

Taschdjian, Claire L., JAMES J. BURCHALL, and Philip J. Kozinn. "Rapid identification of Candida albicans by filamentation on serum and serum substitutes." AMA journal of diseases of children 99.2 (1960): 212–215

Gudlaugsson, Olafur, et al. "Attributable mortality of nosocomial candidemia, revisited." Clinical Infectious Diseases 37.9 (2003): 1172 1177.

Eggimann, Philippe, Jorge Garbino, and Didier Pittet. "Epidemiology of Candida species infections in critically ill non-immunosuppressed patients." The Lancet infectious diseases 3.11 (2003): 685–702.

Wey, Sergio B., et al. "Hospital-acquired candidemia: the attributable mortality and excess length of stay." Archives of internal medicine 148.12 (1988): 2642–2645.

Bish, J.T., and A. Sarachek. "Influences of temperature and adenine concentration upon the cultural instability of a red adenine auxotroph of Candida albicans." Mycologia 59.4 (1967): 671–688.

Poulter, R.U.S.S.E.L.L., et al. "Parasexual genetic analysis of Candida albicans by spheroplast fusion." Journal of Bacteriology 146.3 (1981): 833–840.

Sarachek, Alvin, Douglas D. Rhoads, and Robert H. Schwarzhoff. "Hybridization of Candida albicans through fusion of protoplasts." Archives of Microbiology 129.1 (1981): 1–8.

Magee, B.B., and P.T. Magee. "Induction of mating in Candida albicans by construction of MTL a and MTL α strains." Science 289.5477 (2000): 310–313.

Hull, Christina M., Ryan M. Raisner, and Alexander D. Johnson. "Evidence for mating of the" asexual" yeast Candida albicans in a mammalian host." Science 289.5477 (2000): 307–310.

Bennett, R.J., and A.D. Johnson. "Mating in Candida albicans and the search for a sexual cycle." Annual review of microbiology 59 (2005): 233–256.

Noble, Suzanne M., and Alexander D. Johnson. "Genetics of Candida albicans, a diploid human fungal pathogen." Annu. Rev. Genet. 41 (2007): 193–211.

EDWARDS Jr, JOHN E., et al. "Severe candidal infections: clinical perspective, immune defense mechanisms, and current concepts of therapy." Annals of Internal Medicine 89.1 (1978): 91–106.

Lerner, CHESTER W., and MICHAEL L. Tapper. "Opportunistic infection complicating acquired immune deficiency syndrome. Clinical features of 25 cases." Medicine 63.3 (1984): 155–164.

Munro, Carol A., et al. "Mnt1p and Mnt2p of Candida albicans are partially redundant α-1, 2- mannosyltransferases that participate in O-linked mannosylation and are required for adhesion and virulence." Journal of Biological Chemistry 280.2 (2005): 1051–1060.

Khandelwal, K.R. "Practical Pharmacognosy, Nirali Prakashan, Pune." Edition 2nd (2009): 149–156.

Gawali Vikas, B., et al. "Development and evaluation of polyhebral powder formulation as energy booster." Journal of Pharmacognosy and Phytochemistry 7.3 (2018): 1576–1580.

Bell, L., and T. Labuza. "St. Paul: American Association of Cereal Chemists." (2000): 33–36.

McDonald, Suzy, et al. "Phenolic content and antioxidant activity of olive extracts." Food chemistry 73.1 (2001): 73–84.


Refbacks

  • There are currently no refbacks.


Copyright (c) 2023 Research & Reviews: Journal of Herbal Science