Potential Source of Mesenchymal Stem Cell (MSCs) in Veterinary Medicine

Authors

  • Jyoti Raj Student, Department of Biotechnology, Ghanshyam Singh P.G. College, Varanasi, Uttar Pradesh, India

Keywords:

Animal, clinical, stem cell, veterinary, medicine, therapy

Abstract

Stem cells serve a vital function in veterinary care in a variety of ways. Several stem cell treatments for animal patients are now being developed, and some, such as the treatment of horse tendinopathies using mesenchymal stem cells (MSCs), have already successfully hit the market. Furthermore, animal models are routinely employed to explore the qualities and potential of stem cells for future uses in human health. Furthermore, bovine ES cells have been generated in primary culture, and there have been reports of ES cells obtained from mink, however, practical uses of ES cells are not yet conceivable due to their teratogenic degeneration in vivo. The ability to create a teratoma composed of tissues from all three germ lines also acts as a clear in vivo test for ES. As a result, the focus of veterinary research is presently on adult stem cells and their potential in regenerative medicine. As a result, the goal of this study is to provide an overview of the basic research and clinical applications of MSCs in veterinary medicine.

References

Barry Frank P, Mary Murphy J. Mesenchymal stem cells: clinical applications and biological characterization. Int J Biochem Cell Biol. 2004; 36(4): 568–584.

Fortier LA, et al. Isolation and chondrocytic differentiation of equine bone marrow-derived mesenchymal stem cells. Am J Vet Res. 1998; 59(9): 1182–1187.

Worster Allison A, et al. Effect of transforming growth factor β1 on chondrogenic differentiation of cultured equine mesenchymal stem cells. Am J Vet Res. 2000; 61(9): 1003–1010.

Fortier Lisa A. Stem cells: classifications, controversies, and clinical applications. Vet Surg. 2005;34(5): 415–423.

Koch Thomas G, et al. Isolation of mesenchymal stem cells from equine umbilical cord blood.BMC Biotechnol. 2007; 7(1): 1–9.

Martin Douglas R, et al. Isolation and characterization of multipotential mesenchymal stem cells from feline bone marrow. Exp Hematol. 2002; 30(8): 879–886.

Ringe Jochen, et al. Porcine mesenchymal stem cells. Cell Tissue Res. 2002; 307(3): 321–327.

Bosnakovski Darko, et al. Isolation and multilineage differentiation of bovine bone marrow mesenchymal stem cells. Cell Tissue Res. 2005; 319(2): 243–253.

Reed Sarah A, Johnson Sally E. Equine umbilical cord blood contains a population of stem cells that express Oct4 and differentiate into mesodermal and endodermal cell types. J Cell Physiol. 2008; 215(2): 329–336.

Meirelles Lindolfo da Silva, Pedro Cesar Chagastelles, Nance Beyer Nardi. Mesenchymal stem cells reside in virtually all post-natal organs and tissues. J Cell Sci. 2006; 119(11): 2204–2213.

Fritz J, et al. Biologische Knorpelrekonstruktion im Kniegelenk. Unfallchirurg. 2006; 109(7): 563–576.

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Published

2022-05-24

Issue

Vol. 11 No. 1 (2022)

Section

Review Article

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